Surprising synergy of dual translation inhibition vs. Acinetobacter baumannii and other multidrug-resistant bacterial pathogensResearch in context

Background: Multidrug-resistant (MDR) Acinetobacter baumannii infections have high mortality rates and few treatment options. Synergistic drug combinations may improve clinical outcome and reduce further emergence of resistance in MDR pathogens. Here we show an unexpected potent synergy of two trans...

Full description

Bibliographic Details
Main Authors: Nicholas Dillon, Michelle Holland, Hannah Tsunemoto, Bryan Hancock, Ingrid Cornax, Joe Pogliano, George Sakoulas, Victor Nizet
Format: Article
Language:English
Published: Elsevier 2019-08-01
Series:EBioMedicine
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396419304839