Neonatal exposure to high oxygen levels leads to impaired ischemia-induced neovascularization in adulthood

Abstract Adverse perinatal conditions can lead to developmental programming of cardiovascular diseases. Prematurely born infants are often exposed to high oxygen levels, which in animal models has been associated with endothelial dysfunction, hypertension, and cardiac remodeling during adulthood. He...

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Bibliographic Details
Main Authors: Raphael Mathieu, Sylvie Dussault, Michel Desjarlais, François Rivard, Wahiba Dhahri, Anik Cloutier, Anne-Monique Nuyt, Alain Rivard
Format: Article
Language:English
Published: Nature Publishing Group 2017-10-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-14396-8