Oleoylethanolamide Ameliorates Dextran Sulfate Sodium-Induced Colitis in Rats

Oleoylethanolamide Ameliorates Dextran Sulfate Sodium-Induced Colitis in Rats

Oleoylethanolamide (OEA) is an endogenous fatty acid ethanolamide known for its anti-inflammatory effects and its influence on gut microbiota composition; however, the effects of OEA in inflammatory bowel disease (IBD) remain unknown. During in vitro experiments, OEA downregulated the expression of...

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Bibliographic Details
Main Authors: Shinsuke Otagiri, Shunsuke Ohnishi, Masatsugu Ohara, Qingjie Fu, Koji Yamamoto, Keiko Yamamoto, Takehiko Katsurada, Naoya Sakamoto
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-08-01
Series:Frontiers in Pharmacology
Subjects:
oleoylethanolamide
dextran sulfate sodium
inflammatory bowel disease
nuclear factor kappa B
peroxisome proliferator-activated receptor-α
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2020.01277/full

Internet

https://www.frontiersin.org/article/10.3389/fphar.2020.01277/full

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