Interaction between Metformin, Folate and Vitamin B<sub>12</sub> and the Potential Impact on Fetal Growth and Long-Term Metabolic Health in Diabetic Pregnancies

Interaction between Metformin, Folate and Vitamin B<sub>12</sub> and the Potential Impact on Fetal Growth and Long-Term Metabolic Health in Diabetic Pregnancies

Metformin is the first-line treatment for many people with type 2 diabetes mellitus (T2DM) and gestational diabetes mellitus (GDM) to maintain glycaemic control. Recent evidence suggests metformin can cross the placenta during pregnancy, thereby exposing the fetus to high concentrations of metformin...

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Bibliographic Details
Main Authors: Manon D. Owen, Bernadette C. Baker, Eleanor M. Scott, Karen Forbes
Format: Article
Language:English
Published: MDPI AG 2021-05-01
Series:International Journal of Molecular Sciences
Subjects:
metformin
diabetes
placenta
folate
vitamin B<sub>12</sub>
one carbon metabolism
Online Access:https://www.mdpi.com/1422-0067/22/11/5759

Internet

https://www.mdpi.com/1422-0067/22/11/5759

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