Strategies for Improving siRNA-Induced Gene Silencing Efficiency

Strategies for Improving siRNA-Induced Gene Silencing Efficiency

Purpose: Human telomerase reverse transcriptase (hTERT) plays a crucial role in tumorigenesis and progression of cancers. Gene silencing of hTERT by short interfering RNA (siRNA) is considered as a promising strategy for cancer gene therapy. Various algorithms have been devised for designing a high...

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Bibliographic Details
Main Authors: Fatemeh Safari, Solmaz Rahmani Barouji, Ali Mohammad Tamaddon
Format: Article
Language:English
Published: Tabriz University of Medical Sciences 2017-12-01
Series:Advanced Pharmaceutical Bulletin
Subjects:
RNA Interference
hTERT
Gene silencing
Online Access:http://apb.tbzmed.ac.ir/PDF/apb-7-603.pdf

Internet

http://apb.tbzmed.ac.ir/PDF/apb-7-603.pdf

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