Igf Signaling is Required for Cardiomyocyte Proliferation during Zebrafish Heart Development and Regeneration.

Unlike its mammalian counterpart, the adult zebrafish heart is able to fully regenerate after severe injury. One of the most important events during the regeneration process is cardiomyocyte proliferation, which results in the replacement of lost myocardium. Growth factors that induce cardiomyocyte...

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Bibliographic Details
Main Authors: Ying Huang, Michael R Harrison, Arthela Osorio, Jieun Kim, Aaron Baugh, Cunming Duan, Henry M Sucov, Ching-Ling Lien
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3694143?pdf=render