The G<sub>1 </sub>phase Cdks regulate the centrosome cycle and mediate oncogene-dependent centrosome amplification
<p>Abstract</p> <p>Because centrosome amplification generates aneuploidy and since centrosome amplification is ubiquitous in human tumors, a strong case is made for centrosome amplification being a major force in tumor biogenesis. Various evidence showing that oncogenes and altered...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2011-01-01
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Series: | Cell Division |
Online Access: | http://www.celldiv.com/content/6/1/2 |