A Novel Microfluidic Cell Co-Culture Platform for the Study of the Molecular Mechanisms of Parkinson’s Disease and other Synucleinopathies

A Novel Microfluidic Cell Co-Culture Platform for the Study of the Molecular Mechanisms of Parkinson’s Disease and other Synucleinopathies

Although the precise molecular mechanisms underlying Parkinson’s disease (PD) are still elusive, it is now known that spreading of alpha-synuclein (aSyn) pathology and neuroinflammation are important players in disease progression. Here, we developed a novel microfluidic cell-culture platform for st...

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Bibliographic Details
Main Authors: João Tiago Fernandes, Oldriska Chutna, Virginia Chu, João Pedro Conde, Tiago Fleming Outeiro
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-11-01
Series:Frontiers in Neuroscience
Subjects:
alpha-Synuclein
Inflammation
Microfluidics
Microglia
cell culture
Parkinson’s disease
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnins.2016.00511/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fnins.2016.00511/full

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