A polyepigenetic glucocorticoid exposure score at birth and childhood mental and behavioral disorders

A polyepigenetic glucocorticoid exposure score at birth and childhood mental and behavioral disorders

Background: Maternal depression and anxiety during pregnancy may enhance fetal exposure to glucocorticoids (GCs) and harm neurodevelopment. We tested whether a novel cross-tissue polyepigenetic biomarker indicative of in utero exposure to GC is associated with mental and behavioral disorders and the...

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Bibliographic Details
Main Authors: Anna Suarez, Jari Lahti, Marius Lahti-Pulkkinen, Polina Girchenko, Darina Czamara, Janine Arloth, Anni LK. Malmberg, Esa Hämäläinen, Eero Kajantie, Hannele Laivuori, Pia M. Villa, Rebecca M. Reynolds, Nadine Provençal, Elisabeth B. Binder, Katri Räikkönen
Format: Article
Language:English
Published: Elsevier 2020-11-01
Series:Neurobiology of Stress
Subjects:
Cord blood methylation
Glucocorticoids
Polyepigenetic biomarker
Childhood mental health
Prenatal psychopathology
Prospective study
Online Access:http://www.sciencedirect.com/science/article/pii/S2352289520300655

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http://www.sciencedirect.com/science/article/pii/S2352289520300655

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