High Concentrations of Rosiglitazone Reduce mRNA and Protein Levels of LRP1 in HepG2 Cells
Low-density lipoprotein receptor-related protein 1 (LRP1) is an endocytic receptor involved in the uptake of a variety of molecules, such as apoE, α2-macroglobulin, and the amyloid β peptide (Aβ), for either transcellular transport, protein trafficking or lysosomal degradation. The LRP1 gene can be...
Main Authors: | Alejandro N. Rondón-Ortiz, Christian L. Lino Cardenas, Jimena Martínez-Málaga, Ana L. Gonzales-Urday, Kuljeet S. Gugnani, Mark Böhlke, Timothy J. Maher, Alejandro J. Pino-Figueroa |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2017-11-01
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Series: | Frontiers in Pharmacology |
Subjects: | |
Online Access: | http://journal.frontiersin.org/article/10.3389/fphar.2017.00772/full |
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