Reconstruction of a Genome-Scale Metabolic Model of <i>Streptomyces albus</i> J1074: Improved Engineering Strategies in Natural Product Synthesis

Reconstruction of a Genome-Scale Metabolic Model of <i>Streptomyces albus</i> J1074: Improved Engineering Strategies in Natural Product Synthesis

<i>Streptomyces albus</i> J1074 is recognized as an effective host for heterologous production of natural products. Its fast growth and efficient genetic toolbox due to a naturally minimized genome have contributed towards its advantage in expressing biosynthetic pathways for a diverse r...

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Bibliographic Details
Main Authors: Cheewin Kittikunapong, Suhui Ye, Patricia Magadán-Corpas, Álvaro Pérez-Valero, Claudio J. Villar, Felipe Lombó, Eduard J. Kerkhoven
Format: Article
Language:English
Published: MDPI AG 2021-05-01
Series:Metabolites
Subjects:
genome-scale metabolic model
<i>Streptomyces albus</i> J1074
heterologous production
natural products
gene essentiality
minimized genome
Online Access:https://www.mdpi.com/2218-1989/11/5/304

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https://www.mdpi.com/2218-1989/11/5/304

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