Effects of Dipeptidyl Peptidase-4 Inhibition with MK-0431 on Syngeneic Mouse Islet Transplantation

Dipeptidyl peptidase (DPP)-4 inhibitors increase circulating levels of glucagon-like peptide-1 and glucose-dependent insulinotropic polypeptide which may promote β-cell proliferation and survival. This study tested if DPP-4 inhibition with MK-0431 is beneficial for diabetic mice syngeneically transp...

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Bibliographic Details
Main Authors: Jyuhn-Huarng Juang, Chien-Hung Kuo, Ying-Hsiu Liu, Han-Ying Chang, Chiung-Tong Chen
Format: Article
Language:English
Published: Hindawi Limited 2014-01-01
Series:International Journal of Endocrinology
Online Access:http://dx.doi.org/10.1155/2014/795283