Development of an advanced diagnostic concept for intestinal inflammation: molecular visualisation of nitric oxide in macrophages by functional poly(lactic-co-glycolic acid) microspheres

Development of an advanced diagnostic concept for intestinal inflammation: molecular visualisation of nitric oxide in macrophages by functional poly(lactic-co-glycolic acid) microspheres

We here describe a new approach to visualise nitric oxide (NO) in living macrophages by fluorescent NO-sensitive microspheres based on poly(lactic-co-glycolic acid) (PLGA). PLGA microspheres loaded with NO550 dye were prepared through a modified solvent-evaporation method. Microparticles were charac...

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Bibliographic Details
Main Authors: Kathleen Lange, Christian Lautenschläger, Maria Wallert, Stefan Lorkowski, Andreas Stallmach, Alexander Schiller
Format: Article
Language:English
Published: Beilstein-Institut 2017-08-01
Series:Beilstein Journal of Nanotechnology
Subjects:
functional imaging
intestinal inflammation
microparticle
molecular imaging
nitric oxide
Online Access:https://doi.org/10.3762/bjnano.8.163

Internet

https://doi.org/10.3762/bjnano.8.163

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