Modifying effect of XmnI, BCL11A, and HBS1L-MYB on clinical appearances: A study on β-thalassemia and hemoglobin E/β-thalassemia patients in Indonesia

Objective/background: Thalassemia is a monogenic hematologic disease that has the highest prevalence globally. In addition, there is complexity of the genetic background associated with a variety of phenotypes presented among patients. Genetic heterogeneity related to fetal hemoglobin (HbF) producti...

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Bibliographic Details
Main Authors: Lantip Rujito, Muhammad Basalamah, Wahyu Siswandari, Joko Setyono, Gondo Wulandari, Sri Mulatsih, Abdul Salam M. Sofro, Ahmad Hamim Sadewa, Sutaryo Sutaryo
Format: Article
Language:English
Published: Elsevier 2016-06-01
Series:Hematology/Oncology and Stem Cell Therapy
Online Access:http://www.sciencedirect.com/science/article/pii/S1658387616300036