Multiple pathways coordinating reprogramming of endothelial cells into osteoblasts by BMP4

Multiple pathways coordinating reprogramming of endothelial cells into osteoblasts by BMP4

Summary: Cell type transition occurs during normal development and under pathological conditions. In prostate cancer bone metastasis, prostate cancer-secreted BMP4 induces endothelial cell-to-osteoblast (EC-to-OSB) transition. Such tumor-induced stromal reprogramming supports prostate cancer progres...

Full description

Bibliographic Details
Main Authors: Guoyu Yu, Pengfei Shen, Yu-Chen Lee, Jing Pan, Jian H. Song, Tianhong Pan, Song-Chang Lin, Xin Liang, Guocan Wang, Theocharis Panaretakis, Christopher J. Logothetis, Gary E. Gallick, Li-Yuan Yu-Lee, Sue-Hwa Lin
Format: Article
Language:English
Published: Elsevier 2021-04-01
Series:iScience
Subjects:
Molecular Biology
Cell Biology
Cancer
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004221003564

Internet

http://www.sciencedirect.com/science/article/pii/S2589004221003564

Similar Items