Withania somnifera modulates cancer cachexia associated inflammatory cytokines and cell death in leukaemic THP-1 cells and peripheral blood mononuclear cells (PBMC’s)

Withania somnifera modulates cancer cachexia associated inflammatory cytokines and cell death in leukaemic THP-1 cells and peripheral blood mononuclear cells (PBMC’s)

Abstract Background Cancer and inflammation are associated with cachexia. Withania somnifera (W. somnifera) possesses antioxidant and anti-inflammatory potential. We investigated the potential of an aqueous extract of the root of W. somnifera (WRE) to modulate cytokines, antioxidants and apoptosis i...

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Bibliographic Details
Main Authors: Dhaneshree Bestinee Naidoo, Anil Amichund Chuturgoon, Alisa Phulukdaree, Kanive Parashiva Guruprasad, Kapaettu Satyamoorthy, Vikash Sewram
Format: Article
Language:English
Published: BMC 2018-04-01
Series:BMC Complementary and Alternative Medicine
Subjects:
Cancer
Cachexia
Cytokines
Apoptosis
Withania somnifera
Online Access:http://link.springer.com/article/10.1186/s12906-018-2192-y

Internet

http://link.springer.com/article/10.1186/s12906-018-2192-y

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