Single-step isolation of extracellular vesicles by size-exclusion chromatography

Background: Isolation of extracellular vesicles from plasma is a challenge due to the presence of proteins and lipoproteins. Isolation of vesicles using differential centrifugation or density-gradient ultracentrifugation results in co-isolation of contaminants such as protein aggregates and incomple...

Full description

Bibliographic Details
Main Authors: Anita N. Böing, Edwin van der Pol, Anita E. Grootemaat, Frank A. W. Coumans, Auguste Sturk, Rienk Nieuwland
Format: Article
Language:English
Published: Taylor & Francis Group 2014-09-01
Series:Journal of Extracellular Vesicles
Subjects:
Online Access:http://www.journalofextracellularvesicles.net/index.php/jev/article/download/23430/35574