Vitamin D and Phenylbutyrate Supplementation Does Not Modulate Gut Derived Immune Activation in HIV-1

Vitamin D and Phenylbutyrate Supplementation Does Not Modulate Gut Derived Immune Activation in HIV-1

Dysbiosis and a dysregulated gut immune barrier function contributes to chronic immune activation in HIV-1 infection. We investigated if nutritional supplementation with vitamin D and phenylbutyrate could improve gut-derived inflammation, selected microbial metabolites, and composition of the gut mi...

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Bibliographic Details
Main Authors: Catharina Missailidis, Nikolaj Sørensen, Senait Ashenafi, Wondwossen Amogne, Endale Kassa, Amsalu Bekele, Meron Getachew, Nebiat Gebreselassie, Abraham Aseffa, Getachew Aderaye, Jan Andersson, Susanna Brighenti, Peter Bergman
Format: Article
Language:English
Published: MDPI AG 2019-07-01
Series:Nutrients
Subjects:
HIV-1
vitamin D
phenylbutyrate
clinical trial
TMAO
microbiota
LL-37
kynurenine/tryptophan ratio
Online Access:https://www.mdpi.com/2072-6643/11/7/1675

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https://www.mdpi.com/2072-6643/11/7/1675

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