Efficacy of Dose-Titrated Glucagon Infusions in the Management of Congenital Hyperinsulinism: A Case Series

Efficacy of Dose-Titrated Glucagon Infusions in the Management of Congenital Hyperinsulinism: A Case Series

Background: Congenital hyperinsulinism (CHI), a rare disease of excessive and dysregulated insulin secretion, can lead to prolonged and severe hypoglycemia. Dextrose infusions are a mainstay of therapy to restore normal glycemia, but can be associated with volume overload, especially in infants. By...

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Bibliographic Details
Main Authors: Maria Salomon-Estebanez, Daphne Yau, Mark J. Dunne, Chris Worth, Sune Birch, José L. Walewski, Indraneel Banerjee
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-09-01
Series:Frontiers in Endocrinology
Subjects:
glucose
congenital hyperinsulinism
hypoglycemia
glucagon
infusion
dose titration
Online Access:https://www.frontiersin.org/article/10.3389/fendo.2020.00441/full

Internet

https://www.frontiersin.org/article/10.3389/fendo.2020.00441/full

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