Production of lentiviral vectors with enhanced efficiency to target dendritic cells by attenuating mannosidase activity of mammalian cells
<p>Abstract</p> <p>Background</p> <p>Dendritic cells (DCs) are antigen-presenting immune cells that interact with T cells and have been widely studied for vaccine applications. To achieve this, DCs can be manipulated by lentiviral vectors (LVs) to express antigens to st...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2011-01-01
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Series: | Journal of Biological Engineering |
Online Access: | http://www.jbioleng.org/content/5/1/1 |