Production of lentiviral vectors with enhanced efficiency to target dendritic cells by attenuating mannosidase activity of mammalian cells

<p>Abstract</p> <p>Background</p> <p>Dendritic cells (DCs) are antigen-presenting immune cells that interact with T cells and have been widely studied for vaccine applications. To achieve this, DCs can be manipulated by lentiviral vectors (LVs) to express antigens to st...

Full description

Bibliographic Details
Main Authors: Wang Pin, Joo Kye-Il, Froelich Steven, Tai April
Format: Article
Language:English
Published: BMC 2011-01-01
Series:Journal of Biological Engineering
Online Access:http://www.jbioleng.org/content/5/1/1