Ferumoxytol Attenuates the Function of MDSCs to Ameliorate LPS-Induced Immunosuppression in Sepsis

Abstract Sepsis-induced immunosuppression is recognized as one of the main features responsible for therapeutic failures. Myeloid-derived suppressor cells (MDSCs), which are mainly characterized by their suppressive properties, have been reported to be expanded in sepsis. Ferumoxytol (FMT), an FDA-a...

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Bibliographic Details
Main Authors: Yujun Xu, Yaxian Xue, Xinghan Liu, Yi Li, Huaping Liang, Huan Dou, Yayi Hou
Format: Article
Language:English
Published: SpringerOpen 2019-12-01
Series:Nanoscale Research Letters
Subjects:
FMT
Online Access:https://doi.org/10.1186/s11671-019-3209-2