Functional Role of NRF2 in Cervical Carcinogenesis.

Nuclear factor erythroid-2-related factor 2 (NFE2L2) is a transcription factor associated with resistance to chemotherapy and increased tumor growth. NRF2 is repressed by the inhibitor Keap1. The Keap1-NRF2 pathway is dysfunctional in multiple tumor types. Among Uighur women, the incidence of cervic...

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Bibliographic Details
Main Authors: Jun-Qi Ma, Hatila Tuersun, Shu-Juan Jiao, Jian-He Zheng, Jing-Bao Xiao, Ayshamgul Hasim
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4527737?pdf=render