Evaluating the origin and virulence of a Helicobacter pylori cagA-positive strain isolated from a non-human primate

Evaluating the origin and virulence of a Helicobacter pylori cagA-positive strain isolated from a non-human primate

Abstract Helicobacter pylori cagA-positive strains are critically involved in the development of gastric cancer. Upon delivery into gastric epithelial cells via type IV secretion, the cagA-encoded CagA interacts with and thereby perturbs the pro-oncogenic phosphatase SHP2 and the polarity-regulating...

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Bibliographic Details
Main Authors: Kana Hashi, Chihiro Imai, Koji Yahara, Kamrunnesa Tahmina, Takeru Hayashi, Takeshi Azuma, Takako Miyabe-Nishiwaki, Hideyuki Sato, Masao Matsuoka, Sachi Niimi, Munehiro Okamoto, Masanori Hatakeyama
Format: Article
Language:English
Published: Nature Publishing Group 2018-10-01
Series:Scientific Reports
Subjects:
Pylori cagA-positive Strains
Western CagA
Organoid
CagA Protein
East Asian CagA
Online Access:https://doi.org/10.1038/s41598-018-34425-4

Internet

https://doi.org/10.1038/s41598-018-34425-4

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