Genomic variants in mouse model induced by azoxymethane and dextran sodium sulfate improperly mimic human colorectal cancer

Genomic variants in mouse model induced by azoxymethane and dextran sodium sulfate improperly mimic human colorectal cancer

Abstract Mouse model induced by azoxymethane (AOM) and dextran sodium sulfate (DSS) is generally accepted as an ideal object to study on the carcinogenesis mechanisms of human colorectal cancer (CRC). The genomic responses to the AOM/DSS treatment in mouse that possibly lead to elucidation of CRC pa...

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Bibliographic Details
Main Authors: Qingfei Pan, Xiaomin Lou, Ju Zhang, Yinghui Zhu, Fuqiang Li, Qiang Shan, Xianwei Chen, Yingying Xie, Siyuan Su, Hanfu Wei, Liang Lin, Lin Wu, Siqi Liu
Format: Article
Language:English
Published: Nature Publishing Group 2017-02-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-00057-3

Internet

https://doi.org/10.1038/s41598-017-00057-3

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