The Evolution of Tau Phosphorylation and Interactions

Tau is a neuronal microtubule-associated protein (MAP) that is involved in the regulation of axonal microtubule assembly. However, as a protein with intrinsically disordered regions (IDRs), tau also interacts with many other partners in addition to microtubules. Phosphorylation at selected sites mod...

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Bibliographic Details
Main Authors: Nataliya I. Trushina, Lidia Bakota, Armen Y. Mulkidjanian, Roland Brandt
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-09-01
Series:Frontiers in Aging Neuroscience
Subjects:
tau
Online Access:https://www.frontiersin.org/article/10.3389/fnagi.2019.00256/full