Unsupervised deconvolution of dynamic imaging reveals intratumor vascular heterogeneity and repopulation dynamics.

With the existence of biologically distinctive malignant cells originated within the same tumor, intratumor functional heterogeneity is present in many cancers and is often manifested by the intermingled vascular compartments with distinct pharmacokinetics. However, intratumor vascular heterogeneity...

Full description

Bibliographic Details
Main Authors: Li Chen, Peter L Choyke, Niya Wang, Robert Clarke, Zaver M Bhujwalla, Elizabeth M C Hillman, Ge Wang, Yue Wang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4224420?pdf=render