A Review of the Important Role of <i>CYP2D6 </i>in Pharmacogenomics

A Review of the Important Role of <i>CYP2D6 </i>in Pharmacogenomics

Cytochrome P450 2D6 (<i>CYP2D6</i>) is a critical pharmacogene involved in the metabolism of ~20% of commonly used drugs across a broad spectrum of medical disciplines including psychiatry, pain management, oncology and cardiology. Nevertheless, <i>CYP2D6</i> is highly polymo...

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Bibliographic Details
Main Authors: Christopher Taylor, Ian Crosby, Vincent Yip, Peter Maguire, Munir Pirmohamed, Richard M. Turner
Format: Article
Language:English
Published: MDPI AG 2020-10-01
Series:Genes
Subjects:
CYP2D6
pharmacogenomics
drug metabolism
population variability
structural variation
Online Access:https://www.mdpi.com/2073-4425/11/11/1295

Internet

https://www.mdpi.com/2073-4425/11/11/1295

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