Bone morphogenetic protein dominantly suppresses epidermal growth factor-induced proliferative expansion of adult forebrain neural precursors

Bone morphogenetic protein dominantly suppresses epidermal growth factor-induced proliferative expansion of adult forebrain neural precursors

A single asymmetric division by an adult neural stem cell (NSC) ultimately generates dozens of differentiated progeny, a feat made possible by the proliferative expansion of transit-amplifying progenitor cells (TAPs). Although NSC activation and TAP expansion is determined by pro- and anti-prolifera...

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Bibliographic Details
Main Authors: Sandra Evelyne Joppé, Laura Kerr Hamilton, Loic Mickael Cochard, Louis-Charles eLevros, Anne eAumont, Fanie eBarnabé-Heider, Karl eFernandes
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-10-01
Series:Frontiers in Neuroscience
Subjects:
EGF
adult neurogenesis
BMP
mTOR
Subventricular zone
neural precursors
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnins.2015.00407/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fnins.2015.00407/full

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