A Novel Insecticidal Spider Peptide that Affects the Mammalian Voltage-Gated Ion Channel hKv1.5

A Novel Insecticidal Spider Peptide that Affects the Mammalian Voltage-Gated Ion Channel hKv1.5

Spider venoms include various peptide toxins that modify the ion currents, mainly of excitable insect cells. Consequently, scientific research on spider venoms has revealed a broad range of peptide toxins with different pharmacological properties, even for mammal species. In this work, thirty animal...

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Bibliographic Details
Main Authors: Diana Alvarado, Samuel Cardoso-Arenas, Ligia-Luz Corrales-García, Herlinda Clement, Iván Arenas, Pavel Andrei Montero-Dominguez, Timoteo Olamendi-Portugal, Fernando Zamudio, Agota Csoti, Jesús Borrego, Gyorgy Panyi, Ferenc Papp, Gerardo Corzo
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-01-01
Series:Frontiers in Pharmacology
Subjects:
atrial fibrillation
Kv1.5
Oculicosa supermirabilis
recombinant expression
spider venom
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2020.563858/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2020.563858/full

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