TCR repertoire and CDR3 motif analyses depict the role of αβ T cells in Ankylosing spondylitisResearch in context

TCR repertoire and CDR3 motif analyses depict the role of αβ T cells in Ankylosing spondylitisResearch in context

Background: Ankylosing spondylitis (AS) is a chronic inflammatory disease with worldwide high prevalence. Although AS is strongly associated with HLA-B27 MHC-I antigen presentation, the role played by αβ T cells in AS remains elusive. Methods: Utilizing TCRβ repertoire sequencing and bioinformatics...

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Main Authors: Ming Zheng, Xin Zhang, Yinghui Zhou, Juan Tang, Qing Han, Yang Zhang, Qingshan Ni, Gang Chen, Qingzhu Jia, Haili Yu, Siqi Liu, Elizabeth Robins, Ning Jenny Jiang, Ying Wan, Qi-Jing Li, Zhi-Nan Chen, Ping Zhu
Format: Article
Language:English
Published: Elsevier 2019-09-01
Series:EBioMedicine
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396419304748

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http://www.sciencedirect.com/science/article/pii/S2352396419304748

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