Morphological changes in serotoninergic neurites in the striatum and globus pallidus in levodopa primed MPTP treated common marmosets with dyskinesia

Morphological changes in serotoninergic neurites in the striatum and globus pallidus in levodopa primed MPTP treated common marmosets with dyskinesia

Hyperinnervation of the striatum by serotoninergic (5-HT) terminals occurs after destruction of the dopaminergic nigro-striatal pathway. Recent studies have suggested that non-physiological release of dopamine (DA) formed from levodopa in these serotoninergic terminals underlies abnormal involuntary...

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Bibliographic Details
Main Authors: Bai-Yun Zeng, Mahmoud M. Iravani, Michael J. Jackson, Sarah Rose, André Parent, Peter Jenner
Format: Article
Language:English
Published: Elsevier 2010-12-01
Series:Neurobiology of Disease
Subjects:
Serotonin
Tryptophan hydroxylase
Primate
L-DOPA
Dyskinesia
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996110002561

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http://www.sciencedirect.com/science/article/pii/S0969996110002561

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