Synthesis, Antifungal Evaluation and In Silico Study of N-(4-Halobenzyl)amides

Synthesis, Antifungal Evaluation and In Silico Study of N-(4-Halobenzyl)amides

A collection of 32 structurally related N-(4-halobenzyl)amides were synthesized from cinnamic and benzoic acids through coupling reactions with 4-halobenzylamines, using (benzotriazol-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate (BOP) as a coupling agent. The compounds were identified...

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Bibliographic Details
Main Authors: Ricardo Carneiro Montes, Ana Luiza A. L. Perez, Cássio Ilan S. Medeiros, Marianna Oliveira de Araújo, Edeltrudes de Oliveira Lima, Marcus Tullius Scotti, Damião Pergentino de Sousa
Format: Article
Language:English
Published: MDPI AG 2016-12-01
Series:Molecules
Subjects:
halogenated amides
antimicrobial activity
Candida
vanillic acid derivatives
Online Access:http://www.mdpi.com/1420-3049/21/12/1716

Internet

http://www.mdpi.com/1420-3049/21/12/1716

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