Spinal deformity in aged zebrafish is accompanied by degenerative changes to their vertebrae that resemble osteoarthritis.

Age-related degenerative changes within the vertebral column are a significant cause of morbidity with considerable socio-economic impact worldwide. An improved understanding of these changes through the development of experimental models may lead to improvements in existing clinical treatment optio...

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Bibliographic Details
Main Authors: Anthony J Hayes, Scott Reynolds, Mari A Nowell, Lee B Meakin, Judith Habicher, Johan Ledin, Andrew Bashford, Bruce Caterson, Chrissy L Hammond
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24086633/?tool=EBI