IL-33 Provides Neuroprotection through Suppressing Apoptotic, Autophagic and NF-κB-Mediated Inflammatory Pathways in a Rat Model of Recurrent Neonatal Seizure

IL-33 Provides Neuroprotection through Suppressing Apoptotic, Autophagic and NF-κB-Mediated Inflammatory Pathways in a Rat Model of Recurrent Neonatal Seizure

Interleukin-33 (IL-33) is a novel identified chromatin-associated cytokine of IL-1 family cytokines. It signals through a heterodimer comprised of ST2L and IL-1RAcp, and plays a crucial role in many diseases. However, very little is known about the role and underlying intricate mechanisms of IL-33 i...

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Bibliographic Details
Main Authors: Yuan Gao, Cheng-liang Luo, Li-li Li, Guang-hua Ye, Cheng Gao, Hao-chen Wang, Wen-wen Huang, Tao Wang, Zu-feng Wang, Hong Ni, Xi-ping Chen, Lu-yang Tao
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-12-01
Series:Frontiers in Molecular Neuroscience
Subjects:
apoptosis
autophagy
IL-33
recurrent neonatal seizure
ST2L
Online Access:http://journal.frontiersin.org/article/10.3389/fnmol.2017.00423/full

Internet

http://journal.frontiersin.org/article/10.3389/fnmol.2017.00423/full

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