Gene expression programs in response to hypoxia: cell type specificity and prognostic significance in human cancers.

Gene expression programs in response to hypoxia: cell type specificity and prognostic significance in human cancers.

Inadequate oxygen (hypoxia) triggers a multifaceted cellular response that has important roles in normal physiology and in many human diseases. A transcription factor, hypoxia-inducible factor (HIF), plays a central role in the hypoxia response; its activity is regulated by the oxygen-dependent degr...

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Bibliographic Details
Main Authors: Jen-Tsan Chi, Zhen Wang, Dimitry S A Nuyten, Edwin H Rodriguez, Marci E Schaner, Ali Salim, Yun Wang, Gunnar B Kristensen, Aslaug Helland, Anne-Lise Børresen-Dale, Amato Giaccia, Michael T Longaker, Trevor Hastie, George P Yang, Marc J van de Vijver, Patrick O Brown
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2006-03-01
Series:PLoS Medicine
Online Access:http://europepmc.org/articles/PMC1334226?pdf=render

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http://europepmc.org/articles/PMC1334226?pdf=render

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