Epidermal Growth Factor Receptor Mutations Carried in Extracellular Vesicle-Derived Cargo Mirror Disease Status in Metastatic Non-small Cell Lung Cancer

Epidermal Growth Factor Receptor Mutations Carried in Extracellular Vesicle-Derived Cargo Mirror Disease Status in Metastatic Non-small Cell Lung Cancer

In non-small cell lung cancer (NSCLC), identifying the presence of sensitizing and resistance epidermal growth factor receptor (EGFR) mutations dictates treatment plans. Extracellular vesicles (EVs) are emerging as abundant, stable potential liquid biopsy targets that offer the potential to quantify...

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Bibliographic Details
Main Authors: Emma Purcell, Sarah Owen, Emily Prantzalos, Abigail Radomski, Nayri Carman, Ting-Wen Lo, Mina Zeinali, Chitra Subramanian, Nithya Ramnath, Sunitha Nagrath
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-10-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
extracellular vesicle (EV)
EGFR mutation
longitudinal monitoring
resistance mutation
non-small cell lung cancer
EV-protein
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2021.724389/full

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https://www.frontiersin.org/articles/10.3389/fcell.2021.724389/full

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