Biochemical and Functional Comparisons of mdx and Sgcg−/− Muscular Dystrophy Mouse Models

Mouse models have provided an essential platform to investigate facets of human diseases, from etiology, diagnosis, and prognosis, to potential treatments. Muscular dystrophy (MD) is the most common human genetic disease occurring in approximately 1 in 2500 births. The mdx mouse, which is dystrophin...

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Bibliographic Details
Main Authors: Nathan W. Roberts, Jenan Holley-Cuthrell, Magdalis Gonzalez-Vega, Aaron J. Mull, Ahlke Heydemann
Format: Article
Language:English
Published: Hindawi Limited 2015-01-01
Series:BioMed Research International
Online Access:http://dx.doi.org/10.1155/2015/131436