Investigation of the host transcriptional response to intracellular bacterial infection using Dictyostelium discoideum as a host model

Investigation of the host transcriptional response to intracellular bacterial infection using Dictyostelium discoideum as a host model

Abstract Background During infection by intracellular pathogens, a highly complex interplay occurs between the infected cell trying to degrade the invader and the pathogen which actively manipulates the host cell to enable survival and proliferation. Many intracellular pathogens pose important threa...

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Bibliographic Details
Main Authors: Jonas Kjellin, Maria Pränting, Frauke Bach, Roshan Vaid, Bart Edelbroek, Zhiru Li, Marc P. Hoeppner, Manfred Grabherr, Ralph R. Isberg, Monica Hagedorn, Fredrik Söderbom
Format: Article
Language:English
Published: BMC 2019-12-01
Series:BMC Genomics
Subjects:
Host-pathogen
Infection
High-throughput sequencing
Mycobacteria
Legionella
Dictyostelium discoideum
Online Access:https://doi.org/10.1186/s12864-019-6269-x

Internet

https://doi.org/10.1186/s12864-019-6269-x

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