Synthesis and evaluation of the in vitro and in vivo antitrypanosomal activity of 2-styrylquinolines

In this study, we report the synthesis and evaluation of in vitro and in vivo antitrypanosomal activity of styrylquinoline-like compounds (SQ) 3a-h. Synthesis was carried out by using quinaldine and 8- hydroxyquinaldine with a variety of aromatic aldehydes. The structure of SQs was corroborated by o...

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Bibliographic Details
Main Authors: Roger Espinosa, Sara Robledo, Camilo Guzmán, Natalia Arbeláez, Lina Yepes, Gílmar Santafé, Alex Sáez
Format: Article
Language:English
Published: Elsevier 2021-05-01
Series:Heliyon
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844021011270