Preliminary report on tumor stem cell/B cell hybridoma vaccine for recurrent glioblastoma multiforme

BACKGROUND: Glioblastoma multiforme (GBM), the most aggressive glioma, presents with a rapid evolution and relapse within the first year, which is attributed to the persistence of tumor stem cells (TSC) and the escape of immune surveillance. Mixed leukocyte culture (MLC) cytoimplant has been shown t...

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Bibliographic Details
Main Authors: Gustavo A. Moviglia, Antonio G. Carrizo, Gabriela Varela, Carlos A. Gaeta, Andrea Paes de Lima, Pablo Farina, Hugo Molina
Format: Article
Language:English
Published: Elsevier 2008-01-01
Series:Hematology/Oncology and Stem Cell Therapy
Online Access:http://www.sciencedirect.com/science/article/pii/S1658387608500549