BIAM switch assay coupled to mass spectrometry identifies novel redox targets of NADPH oxidase 4

Aim: NADPH oxidase (Nox) -derived reactive oxygen species have been implicated in redox signaling via cysteine oxidation in target proteins. Although the importance of oxidation of target proteins is well known, the specificity of such events is often debated. Only a limited number of Nox-oxidized p...

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Bibliographic Details
Main Authors: Oliver Löwe, Flávia Rezende, Juliana Heidler, Ilka Wittig, Valeska Helfinger, Ralf P. Brandes, Katrin Schröder
Format: Article
Language:English
Published: Elsevier 2019-02-01
Series:Redox Biology
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231718311339