Efflux-mediated resistance to a benzothiadiazol derivative effective against Burkholderia cenocepacia

Efflux-mediated resistance to a benzothiadiazol derivative effective against Burkholderia cenocepacia

Burkholderia cenocepacia is a major concern for people suffering from Cystic Fibrosis as it contributes to serious respiratory tract infections. The lack of drugs effective against this opportunistic pathogen, along with the high level of resistance to multiple antibiotics, render the treatment of...

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Bibliographic Details
Main Authors: Viola Camilla eScoffone, Olga eRyabova, Vadim eMakarov, Paolo eIadarola, Marco eFumagalli, Marco eFondi, Renato eFani, Edda eDe Rossi, Giovanna eRiccardi, Silvia eBuroni
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-08-01
Series:Frontiers in Microbiology
Subjects:
Burkholderia
Cystic Fibrosis
Drug Resistance
new antimicrobials
efflux pumps
Gram-negatives
Online Access:http://journal.frontiersin.org/Journal/10.3389/fmicb.2015.00815/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fmicb.2015.00815/full

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