Survival motor neuron deficiency enhances progression in an amyotrophic lateral sclerosis mouse model
Mutations in the ubiquitously expressed survival motor neuron 1 (SMN1) and superoxide dismutase 1 (SOD1) genes are selectively lethal to motor neurons in spinal muscular atrophy (SMA) and familial amyotrophic lateral sclerosis (ALS), respectively. Genetic association studies provide compelling evide...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2009-06-01
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Series: | Neurobiology of Disease |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S0969996109000618 |