Resveratrol Protects against Sepsis-Associated Encephalopathy and Inhibits the NLRP3/IL-1β Axis in Microglia

Sepsis-associated encephalopathy (SAE) is characterized as brain dysfunction associated with sepsis. In this study we sought to investigate the effects of resveratrol in mice with SAE, as well as its effects in NLRP3 inflammasome and IL-1β, which were critical in the pathogenesis of SAE. SAE was ind...

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Bibliographic Details
Main Authors: Da-ming Sui, Qun Xie, Wen-jing Yi, Sahil Gupta, Xi-ya Yu, Jin-bao Li, Jun Wang, Jia-feng Wang, Xiao-ming Deng
Format: Article
Language:English
Published: Hindawi Limited 2016-01-01
Series:Mediators of Inflammation
Online Access:http://dx.doi.org/10.1155/2016/1045657