Assessment of sesquiterpene lactones isolated from Mikania plants species for their potential efficacy against Trypanosoma cruzi and Leishmania sp.

Assessment of sesquiterpene lactones isolated from Mikania plants species for their potential efficacy against Trypanosoma cruzi and Leishmania sp.

Four sesquiterpene lactones, mikanolide, deoxymikanolide, dihydromikanolide and scandenolide, were isolated by a bioassay-guided fractionation of Mikania variifolia and Mikania micrantha dichloromethane extracts. Mikanolide and deoxymikanolide were the major compounds in both extracts (2.2% and 0.4%...

Full description

Bibliographic Details
Main Authors: Laura C Laurella, Natacha Cerny, Augusto E Bivona, Andrés Sánchez Alberti, Gustavo Giberti, Emilio L Malchiodi, Virginia S Martino, Cesar A Catalan, María Rosario Alonso, Silvia I Cazorla, Valeria P Sülsen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-09-01
Series:PLoS Neglected Tropical Diseases
Online Access:http://europepmc.org/articles/PMC5629014?pdf=render

Internet

http://europepmc.org/articles/PMC5629014?pdf=render

Similar Items