Novel Omega-3 Fatty Acid Epoxygenase Metabolite Reduces Kidney Fibrosis

Cytochrome P450 (CYP) monooxygenases epoxidize the omega-3 polyunsaturated fatty acid (PUFA) docosahexaenoic acid into novel epoxydocosapentaenoic acids (EDPs) that have multiple biological actions. The present study determined the ability of the most abundant EDP regioisomer, 19,20-EDP to reduce ki...

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Bibliographic Details
Main Authors: Amit Sharma, Md. Abdul Hye Khan, Scott P. Levick, Kin Sing Stephen Lee, Bruce D. Hammock, John D. Imig
Format: Article
Language:English
Published: MDPI AG 2016-05-01
Series:International Journal of Molecular Sciences
Subjects:
Online Access:http://www.mdpi.com/1422-0067/17/5/751