Alpha-synuclein pathology, microgliosis, and parvalbumin neuron loss in the amygdala associated with enhanced fear in the Thy1-aSyn model of Parkinson's disease

In Parkinson's disease (PD), the second most common neurodegenerative disorder, non-motor symptoms often precede the development of debilitating motor symptoms and present a severe impact on the quality of life. Lewy bodies containing misfolded α-synuclein progressively develop in neurons throu...

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Main Authors: Eileen Ruth S. Torres, Milos Stanojlovic, Moriel Zelikowsky, Jana Bonsberger, Sindalana Hean, Caitlin Mulligan, Leonie Baldauf, Sheila Fleming, Eliezer Masliah, Marie-Francoise Chesselet, Michael S. Fanselow, Franziska Richter
Format: Article
Language:English
Published: Elsevier 2021-10-01
Series:Neurobiology of Disease
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Online Access:http://www.sciencedirect.com/science/article/pii/S0969996121002278