The Association of MTHFR C677T and A1298C Polymorphisms with Methotrexate Response and Toxicity in Psoriasis

Background: Methotrexate (MTX) is used to treat psoriasis with various side effects and responsiveness. No predictive indicator of responsivenessor toxicityis available. Objective: Tostudytheassociationof the C677T and A1298C polymorphisms inthe methylenetetrahydrofolate reductase (MTHFR) gene wi...

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Main Authors: Sauvarat Auepemkiate, Anothai Pocathikorn, Pornprot Limprasert, Paramee Thongsuksai, Kanokphorn Chiratikarnwong, Thavatchai Chuaprapaisilp, Sunisa Thaichinda, Panadda Konandana
Format: Article
Language:English
Published: Mahidol University 2016-09-01
Series:Siriraj Medical Journal
Subjects:
Online Access:http://www.smj.si.mahidol.ac.th/sirirajmedj/index.php/smj/article/view/42/42