Genome-Wide Association Study of Metamizole-Induced Agranulocytosis in European Populations

Genome-Wide Association Study of Metamizole-Induced Agranulocytosis in European Populations

Agranulocytosis is a rare yet severe idiosyncratic adverse drug reaction to metamizole, an analgesic widely used in countries such as Switzerland and Germany. Notably, an underlying mechanism has not yet been fully elucidated and no predictive factors are known to identify at-risk patients. With the...

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Bibliographic Details
Main Authors: Anca Liliana Cismaru, Deborah Rudin, Luisa Ibañez, Evangelia Liakoni, Nicolas Bonadies, Reinhold Kreutz, Alfonso Carvajal, Maria Isabel Lucena, Javier Martin, Esther Sancho Ponce, Mariam Molokhia, Niclas Eriksson, EuDAC collaborators, Stephan Krähenbühl, Carlo R. Largiadèr, Manuel Haschke, Pär Hallberg, Mia Wadelius, Ursula Amstutz
Format: Article
Language:English
Published: MDPI AG 2020-10-01
Series:Genes
Subjects:
drug-induced agranulocytosis
metamizole
dipyrone
genome-wide association study
pharmacogenetics
Online Access:https://www.mdpi.com/2073-4425/11/11/1275

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https://www.mdpi.com/2073-4425/11/11/1275

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