Comparison of disease activity in SPMS and PPMS in the context of multicenter clinical trials.

BACKGROUND: Retrospective single center natural history studies have shown that times to reach disability milestones and ages at which they are reached are similar in primary (PPMS) and secondary (SPMS) progressive multiple sclerosis suggesting that they may be phenotypic variations of the same dise...

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Bibliographic Details
Main Authors: Rotem Orbach, Zhenming Zhao, Yong-Cheng Wang, Gilmore O'Neill, Diego Cadavid
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3462180?pdf=render